AMPD3 Antikörper
Kurzübersicht für AMPD3 Antikörper (ABIN6296990)
Target
Alle AMPD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse anti-Human AMPD3 Antibody [Sodium Azide Free]
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Spezifität
- Cytoplasmic, membrane
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Aufreinigung
- Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.
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Immunogen
- Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.
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Applikationshinweise
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Flow Cytometry: 1-2 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL,Immunocytochemistry: 1-2 μg/mL for 30 min at RT
Immunohistology (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
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Andere Bezeichnung
- AMP deaminase 3
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Hintergrund
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Target Description: It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This mAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This mAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
Gene Symbol: AMPD3
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Gen-ID
- 272
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UniProt
- Q01432
Target
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