NADPH Oxidase 4 Antikörper

Produktnummer ABIN6296588

Der Maus Monoklonal Anti-NADPH Oxidase 4-Antikörper wurde für WB, ELISA, FACS, IF und Coat validiert. Er ist geeignet, NADPH Oxidase 4 in Proben von Human zu detektieren.

Kurzübersicht für NADPH Oxidase 4 Antikörper (ABIN6296588)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)

Produktdetails anti-NADPH Oxidase 4 Antikörper

Verwendungszweck: Mouse anti-Human NOX4 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic and cell surface

Aufreinigung: Human recombinant protein was used as the immunogen for this NOX4 antibody.

Immunogen: Human recombinant protein was used as the immunogen for this NOX4 antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL,ELISA: suitable, order BSA-free formulation for coating
WB: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NADPH oxidase 4

Hintergrund:

Target Description: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

Gene Symbol: NOX4///RENOX

Gen-ID: 4821

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration