CD22 Antikörper

Produktnummer ABIN6296528

Der Maus Monoklonal Anti-CD22-Antikörper wurde für FACS, IF und Func validiert. Er ist geeignet, CD22 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CD22 Antikörper (ABIN6296528)

Target: CD22 (CD22 Molecule (CD22))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD22 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Produktdetails anti-CD22 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat CD22 Antibody [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: Human Raji cells were used as the immunogen for the CD22 antibody.

Immunogen: Human Raji cells were used as the immunogen for the CD22 antibody.

Anwendungsinformationen

Applikationshinweise: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD22

Target: CD22 (CD22 Molecule (CD22))

Andere Bezeichnung: B-cell receptor CD22

Hintergrund:

Target Description: Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Gene Symbol: CD22///SIGLEC2

Gen-ID: 933

UniProt: P20273