NEFL Antikörper

Produktnummer ABIN6296239

Dieses Maus Monoklonal-Antikörper erkennt spezifisch NEFL in IHC, IF und FACS. Er zeigt eine Reaktivität gegenüber Human, Ratte, Schwein, Rind (Kuh) und Huhn.

Kurzübersicht für NEFL Antikörper (ABIN6296239)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reaktivität: Human, Ratte, Schwein, Rind (Kuh), Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NEFL Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-NEFL Antikörper

Verwendungszweck: Mouse anti-Human/Rat/Pig/Cow/Chicken Neurofilament Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Crude neurofilament preparation from porcine spinal cord was used as the immunogen for the Neurofilament antibody.

Immunogen: Crude neurofilament preparation from porcine spinal cord was used as the immunogen for the Neurofilament antibody.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Andere Bezeichnung: Neurofilament light polypeptide

Hintergrund:

Target Description: This mAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.

Gene Symbol: NEFL///NF68///NFL

Gen-ID: 4747

UniProt: P07196