S100A8 Antikörper

Produktnummer ABIN6296169

Dieses Anti-S100A8-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von S100A8 in IHC, IF und FACS. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Cat, Affe, Pferd, Meerschweinchen, Pavian und Ziege.

Kurzübersicht für S100A8 Antikörper (ABIN6296169)

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Cat, Affe, Pferd, Meerschweinchen, Pavian, Ziege

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100A8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-S100A8 Antikörper

Verwendungszweck: Mouse anti-Human/Baboon/Monkey/Cow/Pig/Goat/Horse/Cat/Dog/Rabbit/Guinea Pig/Rat/Mouse Macrophage Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: An affinity purified monocyte membrane preparation was used as the immunogen for the anti-Macrophage antibody.

Immunogen: An affinity purified monocyte membrane preparation was used as the immunogen for the anti-Macrophage antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu S100A8

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Andere Bezeichnung: Protein S100-A8

Hintergrund:

Target Description: Recognizes the macrophage L1 protein Calprotectin, expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This mAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.

Gene Symbol: S100A8///CAGA///CFAG///MRP8///S100A9///CAGB///CFAG///MRP14

UniProt: P05109, P06702

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine