Cadherin-16 Antikörper

Produktnummer ABIN6296087

Der Kaninchen Polyklonal Anti-Cadherin-16-Antikörper wurde für IHC, IF und FACS validiert. Er ist geeignet, Cadherin-16 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Cadherin-16 Antikörper (ABIN6296087)

Target: Cadherin-16 (CDH16)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin-16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Cadherin-16 Antikörper

Verwendungszweck: Rabbit anti-Human/Mouse/Rat Cadherin 16 Antibody [Sodium Azide Free]

Spezifität: Cell surface with some cytoplasmic

Aufreinigung: A recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

Immunogen: A recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10e6 cells
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Cadherin-16

Target: Cadherin-16 (CDH16)

Andere Bezeichnung: Cadherin-16

Hintergrund:

Target Description: Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Gene Symbol: CDH16///UNQ695///PRO1340

Gen-ID: 1014

UniProt: O75309