PD-1 Antikörper

Produktnummer ABIN6295971

Der Kaninchen Polyklonal anti-PD-1 Antikörper (ABIN6295971) detektiert spezifisch PD-1 in FACS, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PD-1 Antikörper (ABIN6295971)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PD-1 Antikörper

Verwendungszweck: Rabbit anti-Human PDCD1 / PD-1 Antibody [Sodium Azide Free]

Spezifität: Cell surface & cytoplasmic

Aufreinigung: A full-length human protein was used as the immunogen for the PD1 antibody.

Immunogen: A full-length human protein was used as the immunogen for the PD1 antibody.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
Immunofluorescence: 1-2 μg/mL
FACS: 0.5-1 μg/10e6 cells in 0.1ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: Programmed cell death protein 1

Hintergrund:

Target Description: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

Gene Symbol: PDCD1///PD1

Gen-ID: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints