PODXL Antikörper (Extracellular Domain)

Produktnummer ABIN6295450

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PODXL in WB, IHC, IP, FACS und IF. Er zeigt eine Reaktivität gegenüber Human, Ratte und Kaninchen.

Kurzübersicht für PODXL Antikörper (Extracellular Domain) (ABIN6295450)

Target: PODXL (Podocalyxin-Like (PODXL))

Reaktivität: Human, Ratte, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PODXL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-PODXL Antikörper

Bindungsspezifität: Extracellular Domain

Verwendungszweck: Mouse anti-Human/Rabbit/Rat Podocalyxin Antibody [Sodium Azide Free]

Spezifität: Cell surface and cytoplasmic

Aufreinigung: A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.

Immunogen: A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IP: 1-2 μg/500 μg protein
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Andere Bezeichnung: Podocalyxin

Hintergrund:

Target Description: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Gene Symbol: PODXL///PCLP///PCLP1

Gen-ID: 5420

UniProt: O00592

Pathways: Tube Formation