PINK1 Antikörper (Center)

Produktnummer ABIN6295262

Der Kaninchen Polyklonal Anti-PINK1-Antikörper wurde für validiert. Er ist geeignet, PINK1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für PINK1 Antikörper (Center) (ABIN6295262)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PINK1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-PINK1 Antikörper

Bindungsspezifität: AA 237-266, Center

Verwendungszweck: Rabbit Anti-PINK1 (PARK6) (Center) Antibody

Immunogen: This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human PINK1 (PARK6).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Andere Bezeichnung: PINK1

Hintergrund:

Target Description: Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.

Gene Symbol: PINK1

Gen-ID: 65018

UniProt: Q9BXM7

Pathways: Autophagie