KRT6A Antikörper (C-Term)

Produktnummer ABIN6294643

Dieses Maus Monoklonal-Antikörper erkennt spezifisch KRT6A in IHC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für KRT6A Antikörper (C-Term) (ABIN6294643)

Target: KRT6A (Keratin 6A (KRT6A))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT6A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-KRT6A Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mouse anti-Human/Mouse Cytokeratin 6 Antibody [IHC only]

Spezifität: Cytoplasmic

Aufreinigung: A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from the C-terminus of human Cytokeratin 6 was used as the immunogen for this antibody.

Immunogen: A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from the C-terminus of human Cytokeratin 6 was used as the immunogen for this antibody.

Anwendungsinformationen

Applikationshinweise: Prediluted format : incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Andere Bezeichnung: Keratin, type II cytoskeletal 6A

Hintergrund:

Target Description: This antibody recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6) or Keratin 6. In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express Cytokeratin 6 and 16. Keratin 6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of Cytokeratin 6 is particularly associated with differentiation.

Gene Symbol: KRT6A///K6A///KRT6D

Gen-ID: 3853

UniProt: P02538