CD79a Antikörper (AA 202-216)

Produktnummer ABIN6294396

Dieses Anti-CD79a-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD79a in IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein und Affe.

Kurzübersicht für CD79a Antikörper (AA 202-216) (ABIN6294396)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD79a Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-CD79a Antikörper

Bindungsspezifität: AA 202-216

Verwendungszweck: Rabbit anti-Human/Mouse/Rat/Monkey/Pig/Cow Recombinant CD79a Antibody [IHC only]

Spezifität: Cell surface, cytoplasmic

Aufreinigung: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.

Immunogen: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.

Anwendungsinformationen

Applikationshinweise: Prediluted IHC only format: incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Andere Bezeichnung: B-cell antigen receptor complex-associated protein alpha chain

Hintergrund:

Target Description: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

Gene Symbol: CD79A///IGA///MB1

Gen-ID: 973

UniProt: P11912

Pathways: BCR Signaling