KIT Antikörper (AA 100-300)

Produktnummer ABIN6294267

Der Maus Monoklonal anti-KIT Antikörper (ABIN6294267) detektiert spezifisch KIT in WB, FACS, IF und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KIT Antikörper (AA 100-300) (ABIN6294267)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-KIT Antikörper

Bindungsspezifität: AA 100-300

Verwendungszweck: Mouse anti-Human c-Kit Antibody [Sodium Azide Free]

Spezifität: Cell surface and cytoplasmic

Aufreinigung: A recombinant human fragment around amino acids 100-300 was used as the immunogen for the c-Kit antibody.

Immunogen: A recombinant human fragment around amino acids 100-300 was used as the immunogen for the c-Kit antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: (0.5-1 μg/mL for 2 hours at RT)
Immunohistochemistry (Frozen Only): 2-4 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: Mast/stem cell growth factor receptor Kit

Hintergrund:

Target Description: This mAb recognizes a protein of 145 kDa, identified as CD117/p145kit/c-Kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117/c-Kit has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117/c-Kit is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Gene Symbol: KIT///SCFR

Gen-ID: 3815

UniProt: P10721

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity