CRYBA1 Antikörper

Produktnummer ABIN6291831

Dieses Anti-CRYBA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CRYBA1 in WB. Geeignet für Maus und Ratte.

Kurzübersicht für CRYBA1 Antikörper (ABIN6291831)

Target: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYBA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRYBA1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CRYBA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu CRYBA1

Target: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Andere Bezeichnung: CRYBA1

Hintergrund: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'.

Molekulargewicht: 25.15 kDa

Gen-ID: 1411

UniProt: P05813