CRYBA1 Antikörper (Middle Region)

Produktnummer ABIN950651

Produktdetails anti-CRYBA1 Antikörper

Target: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Bindungsspezifität: AA 111-141, Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYBA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse Beta-crystallin A3.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 111-141 amino acids from the Central region of Human CRYBA1. Genename: CRYBA1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CRYBA1

Target: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Andere Bezeichnung: beta-Crystallin A3 (CRYBA1 Produkte)

Synonyme: CRYB1 antikoerper, CTRCT10 antikoerper, BA3/A1 antikoerper, Cryb antikoerper, BA3A1C antikoerper, beta-A3 antikoerper, cryba1 antikoerper, zgc:92688 antikoerper, CRYBA3 antikoerper, cryb1 antikoerper, zgc:92720 antikoerper, crystallin beta A1 antikoerper, crystallin, beta A1 antikoerper, crystallin, beta A1a antikoerper, crystallin beta A1 L homeolog antikoerper, crystallin, beta A1b antikoerper, CRYBA1 antikoerper, Cryba1 antikoerper, cryba1a antikoerper, cryba1.L antikoerper, cryba1 antikoerper, cryba1b antikoerper

Hintergrund: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'Synonyms: CRYB1, CRYBA1

Molekulargewicht: 25150 Da

Gen-ID: 1411

NCBI Accession: NP_005199