STEAP4 Antikörper (C-Term)

Produktnummer ABIN6265335

Der Kaninchen Polyklonal Anti-STEAP4-Antikörper wurde für ELISA, IHC, WB, IF und ICC validiert. Er ist geeignet, STEAP4 in Proben von Human zu detektieren.

Kurzübersicht für STEAP4 Antikörper (C-Term) (ABIN6265335)

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-STEAP4 Antikörper

Bindungsspezifität: C-Term

Spezifität: STEAP4 Antibody detects endogenous levels of total STEAP4.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human STEAP4, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200, IF/ICC 1:100-1:500, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu STEAP4

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Andere Bezeichnung: STEAP4

Hintergrund:

Description: Metalloreductase that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+ (By similarity). Uses NADP+ as acceptor (By similarity). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance (PubMed:18430367, PubMed:18381574). Involved in inflammatory arthritis, through the regulation of inflammatory cytokines (PubMed:19660107). Inhibits anchorage-independent cell proliferation (PubMed:19787193).

Gene: STEAP4

Molekulargewicht: 51kDa

Gen-ID: 79689

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis