SOCS2 Antikörper (C-Term)
Kurzübersicht für SOCS2 Antikörper (C-Term) (ABIN6265216)
Target
Alle SOCS2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- SOCS2 Antibody
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Spezifität
- SOCS2 Antibody detects endogenous levels of total SOCS2
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Homologie
- Pig,Bovine,Sheep,Rabbit,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human SOCS2, corresponding to a region within C-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:200-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
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Andere Bezeichnung
- SOCS2
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Hintergrund
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Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Gene: SOCS2
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Molekulargewicht
- 23 kDa
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Gen-ID
- 8835
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UniProt
- O14508
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Pathways
- JAK-STAT Signalweg, Response to Growth Hormone Stimulus
Target
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