Lysine (K)-Specific Methyltransferase 2B (KMT2B) (Internal Region) Antikörper
Kurzübersicht für Lysine (K)-Specific Methyltransferase 2B (KMT2B) (Internal Region) Antikörper (ABIN6263280)
Target
Alle Lysine (K)-Specific Methyltransferase 2B (KMT2B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- MLL2 Antibody detects endogenous levels of total MLL2.
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Homologie
- Pig,Bovine,Sheep,Rabbit,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human MLL2, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-3000, IHC 1:50-200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- Lysine (K)-Specific Methyltransferase 2B (KMT2B)
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Andere Bezeichnung
- KMT2D
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Hintergrund
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Description: Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.
Gene: KMT2D
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Molekulargewicht
- 593kDa
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Gen-ID
- 8085
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UniProt
- O14686
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Pathways
- Warburg Effekt
Target
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