MAD1L1 Antikörper (N-Term)

Produktnummer ABIN6263047

Produktdetails anti-MAD1L1 Antikörper

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAD1L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: MAD1L1 Antibody detects endogenous levels of total MAD1L1.

Homologie: Pig,Bovine,Horse,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAD1L1, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MAD1L1

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Andere Bezeichnung: MAD1L1 (MAD1L1 Produkte)

Synonyme: MAD1 antikoerper, PIG9 antikoerper, TP53I9 antikoerper, TXBP181 antikoerper, AI173502 antikoerper, AW550425 antikoerper, Mad1 antikoerper, zgc:56571 antikoerper, MAD1-like protein 1 antikoerper, mitotic arrest deficient 1 like 1 antikoerper, MAD1 mitotic arrest deficient like 1 antikoerper, MAD1 mitotic arrest deficient 1-like 1 antikoerper, deafness, autosomal recessive 19 antikoerper, MAD1L1 antikoerper, Mad1l1 antikoerper, mad1l1 antikoerper, DFNB19 antikoerper

Hintergrund:

Description: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.

Gene: MAD1L1

Molekulargewicht: 83kDa

Gen-ID: 8379

UniProt: Q9Y6D9

Pathways: M Phase