Hepcidin Antikörper (Internal Region)

Produktnummer ABIN6262147

Dieses Anti-Hepcidin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Hepcidin in WB, IHC und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Hepcidin Antikörper (Internal Region) (ABIN6262147)

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hepcidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Hepcidin Antikörper

Bindungsspezifität: Internal Region

Spezifität: HAMP Antibody detects endogenous levels of total HAMP.

Homologie: Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HAMP, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: HAMP

Hintergrund:

Description: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).

Gene: HAMP

Molekulargewicht: 9kDa

Gen-ID: 57817

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis