ENOS Antikörper (C-Term)

Produktnummer ABIN6261536

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ENOS in WB, ELISA, IHC, IF und ICC. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für ENOS Antikörper (C-Term) (ABIN6261536)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-ENOS Antikörper

Bindungsspezifität: C-Term

Spezifität: ENOS Antibody detects endogenous levels of total eNOS.

Homologie: Pig,Bovine,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human eNOS, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-ENOS Antikörper (ABIN6261536)

Hu, Cheng, Huang, Cai, Lian, Wang, Gao: "Effects of Xin-Ji-Er-Kang on heart failure induced by myocardial infarction: Role of inflammation, oxidative stress and endothelial dysfunction." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 42, pp. 245-257, (2018) (PubMed).

Ruan, Ren, Zhang, Zhu, Xu, Wang: "Cardioprotective Effects of QiShenYiQi Dripping Pills on Transverse Aortic Constriction-Induced Heart Failure in Mice." in: Frontiers in physiology, Vol. 9, pp. 324, (2018) (PubMed).

Zhu, Hu, Lv, Cheng, Gao: "Effects of oligomeric grape seed proanthocyanidins on L-NAME-induced hypertension in pregnant mice: Role of oxidative stress and endothelial dysfunction." in: Phytotherapy research : PTR, Vol. 32, Issue 9, pp. 1836-1847, (2018) (PubMed).

Li, Wang, Zha, Cao, Sheng, Chen: "SIRT1 inhibits TGF-β-induced endothelial-mesenchymal transition in human endothelial cells with Smad4 deacetylation." in: Journal of cellular physiology, (2018) (PubMed).

Lu, Wang, Wang, Zhang, Liu, Zhang, Geng, Shan: "Beneficial effects of renal denervation on cardiac angiogenesis in rats with prolonged pressure overload." in: Acta physiologica (Oxford, England), Vol. 220, Issue 1, pp. 47-57, (2017) (PubMed).

Details zu ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Andere Bezeichnung: NOS3

Hintergrund:

Description: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Gene: NOS3

Molekulargewicht: 140kDa

Gen-ID: 4846

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling