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Centriolin Antikörper

CNTRL Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260763
  • Target Alle Centriolin (CNTRL) Antikörper anzeigen
    Centriolin (CNTRL)
    Reaktivität
    • 13
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 13
    Kaninchen
    Klonalität
    • 13
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Centriolin Antikörper ist unkonjugiert
    Applikation
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    CEP110 Antibody detects endogenous levels of total CEP110
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CEP110
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:1000-3000 IHC 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    Centriolin (CNTRL)
    Andere Bezeichnung
    CEP110 (CNTRL Produkte)
    Synonyme
    CEP1 antikoerper, CEP110 antikoerper, FAN antikoerper, bA165P4.1 antikoerper, Cep1 antikoerper, Cep110 antikoerper, 6720467O09Rik antikoerper, AA968343 antikoerper, Cntrl antikoerper, IB3/5 antikoerper, Ma2a8 antikoerper, b2b1468Clo antikoerper, centriolin antikoerper, CNTRL antikoerper, Cntrl antikoerper
    Hintergrund

    Description: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).

    Gene: CCP110

    Molekulargewicht
    113kDa
    Gen-ID
    9738
    UniProt
    O43303
    Pathways
    M Phase, SARS-CoV-2 Protein Interaktom
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