Centriolin Antikörper (AA 850-900)

Produktnummer ABIN1451145

Der Kaninchen Polyklonal anti-Centriolin Antikörper (ABIN1451145) detektiert spezifisch Centriolin in ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Centriolin Antikörper (AA 850-900) (ABIN1451145)

Target: Centriolin (CNTRL)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Centriolin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Centriolin Antikörper

Bindungsspezifität: AA 850-900

Verwendungszweck: Centriolin Antibody

Spezifität: Centriolin Polyclonal Antibody detects endogenous levels of Centriolin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CEP110. AA range:850-900

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Centriolin

Target: Centriolin (CNTRL)

Andere Bezeichnung: CEP110

Hintergrund:

Synonyms: CCP110, CEP110, CP110, KIAA0419, Centriolar coiled-coil protein of 110 kDa, Centrosomal protein of 110 kDa, CP110, Cep110

Background: function:Necessary for centrosome duplication. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.,induction:Up-regulated during the transition from G1 to S phase of the cell cycle. The highest levels are observed in S phase, after which the levels decrease markedly.,PTM:Phosphorylated by CDKs.,subunit:Interacts with CALM1, CETN2 and CEP97.,tissue specificity:Highly expressed in testis. Detected at intermediate levels in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.,

Gene Name: CCP110

Protein Name: Centriolar coiled-coil protein of 110 kDa

Molekulargewicht: 113 kDa

Gen-ID: 9738

OMIM: 609544

UniProt: O43303

Pathways: M Phase, SARS-CoV-2 Protein Interaktom