ATG4A Antikörper (N-Term)
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- Target Alle ATG4A Antikörper anzeigen
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATG4A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- ATG4A Antibody detects endogenous levels of total ATG4A.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ATG4A, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ATG4A Primärantikörper
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anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 258-398) antibody
ATG4A Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 8C9C2 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 363-392) antibodyATG4A Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB7555 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 258-398) antibodyATG4A Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 8E8G2 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 82-111) antibodyATG4A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7553 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 369-398), (C-Term) antibodyATG4A Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 51-150) antibodyATG4A Reaktivität: Human, Maus, Ratte ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) antibodyATG4A Reaktivität: Human WB, IHC (p), IF, IF (cc) Wirt: Maus Monoclonal 14C9 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 1-30) antibodyATG4A Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB7493 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 1-214) antibodyATG4A Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (Internal Region) antibodyVerified ATG4A Reaktivität: Human ELISA, IHC Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Andere Bezeichnung
- ATG4A (ATG4A Produkte)
- Hintergrund
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Description: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Gene: ATG4A
- Molekulargewicht
- 45 kDa
- Gen-ID
- 115201
- UniProt
- Q8WYN0
- Pathways
- Autophagie
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