MYBL1 Antikörper (Internal Region)

Produktnummer ABIN6259660

Dieses Anti-MYBL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MYBL1 in WB, ELISA, ICC und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MYBL1 Antikörper (Internal Region) (ABIN6259660)

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-MYBL1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: A-Myb Antibody detects endogenous levels of total A-Myb.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human A-Myb, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MYBL1

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Andere Bezeichnung: MYBL1

Hintergrund:

Description: Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:8058310, PubMed:7987850). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity).

Gene: MYBL1

Molekulargewicht: 85kDa

Gen-ID: 4603

UniProt: P10243

Pathways: Zellzyklus, Chromatin Binding