IL12RB1 Antikörper (Internal Region)
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- Target Alle IL12RB1 Antikörper anzeigen
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL12RB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- IL12RB1 Antibody detects endogenous levels of total IL12RB1.
- Homologie
- Bovine
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IL12RB1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product IL12RB1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- Andere Bezeichnung
- IL12RB1 (IL12RB1 Produkte)
- Hintergrund
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Description: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Gene: IL12RB1
- Molekulargewicht
- 73 kDa
- Gen-ID
- 3594
- UniProt
- P42701
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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