PHLDA3 Antikörper (C-Term)
Kurzübersicht für PHLDA3 Antikörper (C-Term) (ABIN6258301)
Target
Alle PHLDA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- PHLDA3 Antibody detects endogenous levels of total PHLDA3.
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Homologie
- Pig,Rabbit
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human PHLDA3, corresponding to a region within C-terminal amino acids.
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Isotyp
- IgG
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anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) antibody
PHLDA3 Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (AA 1-31), (N-Term) antibodyPHLDA3 Reaktivität: Human WB Wirt: Maus Monoclonal 4B6 unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (Internal Region) antibodyPHLDA3 Reaktivität: Human ELISA, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (AA 43-95) antibodyPHLDA3 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (Internal Region) antibodyPHLDA3 Reaktivität: Human, Maus, Ratte ELISA, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (C-Term) antibodyVerified PHLDA3 Reaktivität: Human ELISA, WB Wirt: Ziege Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (AA 38-87) antibodyPHLDA3 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (N-Term) antibodyPHLDA3 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (Internal Region) antibodyPHLDA3 Reaktivität: Human, Maus, Ratte ELISA, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Haltbarkeit
- 12 months
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- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
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Andere Bezeichnung
- PHLDA3
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Hintergrund
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Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Gene: PHLDA3
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Molekulargewicht
- 14 kDa
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Gen-ID
- 23612
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UniProt
- Q9Y5J5
Target
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