SHB Antikörper (C-Term)

Produktnummer ABIN6257494

Dieses Anti-SHB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SHB in WB, ELISA, ICC und IF. Geeignet für Human und Maus.

Kurzübersicht für SHB Antikörper (C-Term) (ABIN6257494)

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-SHB Antikörper

Bindungsspezifität: C-Term

Spezifität: SHB Antibody detects endogenous levels of total SHB.

Homologie: Pig,Bovine,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SHB, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SHB

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Andere Bezeichnung: SHB

Hintergrund:

Description: Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Gene: SHB

Molekulargewicht: 55 kDa

Gen-ID: 6461

UniProt: Q15464