BARD1 Antikörper (Internal Region)
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- Target Alle BARD1 Antikörper anzeigen
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BARD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- BARD1 Antibody detects endogenous levels of total BARD1.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human BARD1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product BARD1 Primärantikörper
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anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 101-200) antibody
BARD1 Reaktivität: Human WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 658-757) antibodyBARD1 Reaktivität: Human ELISA, IF Wirt: Maus Monoclonal 2A11 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 428-777) antibodyBARD1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 101-131), (N-Term) antibodyBARD1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB19063 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 Reaktivität: Human WB, IP, DB Wirt: Maus Monoclonal 2059C4a unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
- Andere Bezeichnung
- BARD1 (BARD1 Produkte)
- Hintergrund
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Description: E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
Gene: BARD1
- Molekulargewicht
- 79 kDa
- Gen-ID
- 580
- UniProt
- Q99728
- Pathways
- DNA Reparatur
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