STAT5A Antikörper (pTyr694)
Kurzübersicht für STAT5A Antikörper (pTyr694) (ABIN6256791)
Target
Alle STAT5A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr694
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Spezifität
- Phospho-STAT5A (Tyr694) Antibody detects endogenous levels of STAT5A only when phosphorylated at Tyrosine 694
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human STAT5A around the phosphorylation site of Tyrosine 694
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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Andere Bezeichnung
- STAT5A
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Hintergrund
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Description: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Gene: STAT5A
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Molekulargewicht
- 90kDa
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Gen-ID
- 6776
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UniProt
- P42229, P51692
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Pathways
- JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
Target
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