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HSP27 Antikörper (pSer15)

HSPB1 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256149
  • Target Alle HSP27 (HSPB1) Antikörper anzeigen
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    Bindungsspezifität
    • 42
    • 37
    • 26
    • 16
    • 16
    • 10
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer15
    Reaktivität
    • 299
    • 103
    • 89
    • 24
    • 14
    • 14
    • 13
    • 12
    • 11
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 237
    • 66
    Kaninchen
    Klonalität
    • 206
    • 96
    Polyklonal
    Konjugat
    • 137
    • 23
    • 17
    • 13
    • 12
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HSP27 Antikörper ist unkonjugiert
    Applikation
    • 256
    • 104
    • 103
    • 94
    • 69
    • 49
    • 49
    • 46
    • 41
    • 40
    • 16
    • 12
    • 10
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Phospho-HSP27 (Ser15) Antibody detects endogenous levels of HSP27 only when phosphorylated at Serine 15.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human HSP27 around the phosphorylation site of Ser15.
    Isotyp
    IgG
    Top Product
    Discover our top product HSPB1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, pH 7.4,50 % glycerol.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Xia, Yao, Tang, Xiao, Yang, Zhou: "Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Hugan Qingzhi and Its Protective Properties against Free Fatty Acid-Induced L02 Hepatocyte Injury." in: Frontiers in pharmacology, Vol. 8, pp. 99, (2017) (PubMed).

  • Target
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    Andere Bezeichnung
    HSPB1 (HSPB1 Produkte)
    Synonyme
    CMT2F antikoerper, HMN2B antikoerper, HS.76067 antikoerper, HSP27 antikoerper, HSP28 antikoerper, Hsp25 antikoerper, SRP27 antikoerper, 27kDa antikoerper, Hsp27 antikoerper, cb153 antikoerper, cb660 antikoerper, hsp1 antikoerper, hsp25 antikoerper, hsp27 antikoerper, id:ibd2821 antikoerper, sb:cb660 antikoerper, zgc:103437 antikoerper, HSPB1 antikoerper, cmt2f antikoerper, hs.76067 antikoerper, hsp28 antikoerper, heat shock protein family B (small) member 1 antikoerper, heat shock protein 1 antikoerper, heat shock protein, alpha-crystallin-related, 1 antikoerper, heat shock protein family B (small) member 1 L homeolog antikoerper, HSPB1 antikoerper, Hspb1 antikoerper, hspb1 antikoerper, hspb1.L antikoerper
    Hintergrund

    Description: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).

    Gene: HSPB1

    Molekulargewicht
    27kDa
    Gen-ID
    3315
    UniProt
    P04792
    Pathways
    MAPK Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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