EPOR Antikörper (pTyr368)
Kurzübersicht für EPOR Antikörper (pTyr368) (ABIN6255901)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr368
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Spezifität
- Phospho-Epo-R (Tyr368) Antibody detects endogenous levels of Epo-R only when phosphorylated at Tyrosine 368.
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Homologie
- Pig,Sheep,Dog
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Epo-R around the phosphorylation site of Tyr368.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- EPOR (Erythropoietin Receptor (EPOR))
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Andere Bezeichnung
- EPOR
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Hintergrund
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Description: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Gene: EPOR
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Molekulargewicht
- 55kDa
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Gen-ID
- 2057
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UniProt
- P19235
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Pathways
- JAK-STAT Signalweg
Target
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