EPOR Antikörper (AA 32-225)

Produktnummer ABIN5693050

Der Kaninchen Polyklonal anti-EPOR Antikörper wird verwendet zum Nachweis von EPOR in Proben von Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für EPOR Antikörper (AA 32-225) (ABIN5693050)

Target: EPOR (Erythropoietin Receptor (EPOR))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPOR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-EPOR Antikörper

Bindungsspezifität: AA 32-225

Verwendungszweck: Anti-EPO Receptor/Epor Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-EPO Receptor/Epor Antibody (ABIN5693050). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Immunogen: E. coli-derived mouse EPO Receptor recombinant protein (Position: D32-E225).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu EPOR

Target: EPOR (Erythropoietin Receptor (EPOR))

Andere Bezeichnung: Epor

Hintergrund:

Synonyms: Erythropoietin receptor, EPO-R, Epor

Tissue Specificity: Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells.

Background: The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 55 kDa

Gen-ID: 13857

UniProt: P14753

Pathways: JAK-STAT Signalweg