ATG13 Antikörper (pSer355)
Kurzübersicht für ATG13 Antikörper (pSer355) (ABIN6255252)
Target
Alle ATG13 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer355
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Spezifität
- Phospho-Atg13 (Ser355) Antibody detects endogenous levels of Atg13.
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Atg13 around the phosphorylation site of Ser355.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- ATG13 (Autophagy Related 13 (ATG13))
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Andere Bezeichnung
- Atg13
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Hintergrund
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Description: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Gene: ATG13
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Molekulargewicht
- 72kDa
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Gen-ID
- 9776
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UniProt
- O75143
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Pathways
- PI3K-Akt Signalweg, Autophagie
Target
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