Annexin A2 Antikörper (pSer26)
Kurzübersicht für Annexin A2 Antikörper (pSer26) (ABIN6255139)
Target
Alle Annexin A2 (ANXA2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer26
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Spezifität
- Phospho-Annexin A2 (Ser26) Antibody detects endogenous levels of Annexin A2 only when phosphorylated at Ser26.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Annexin A2 around the phosphorylation site of Ser26.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- Annexin A2 (ANXA2)
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Andere Bezeichnung
- ANXA2
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Hintergrund
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Description: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).
Gene: ANXA2
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Molekulargewicht
- 37 kDa
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Gen-ID
- 302
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UniProt
- P07355
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Pathways
- S100 Proteine
Target
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