beta Catenin Antikörper (C-Term)
Kurzübersicht für beta Catenin Antikörper (C-Term) (ABIN6254224)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Anti-beta-Catenin
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Sequenz
- MDPMMEHEMG GHHPGADYPV DGLPDLGHAQ DLMDGLPPGD SNQLAWFDTD L
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Spezifität
- Detects a band of approximately 95 kDa by Western blot in MNT1 and SH-SY5Y cell lysates.
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Produktmerkmale
- Catenin (cadherin-associated protein), beta 1, 88 kDa
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Aufreinigung
- Epitope affinity purified
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Immunogen
- Purified recombinant peptide derived from within residues 731 aa to the C-terminus of human beta Catenin produced in E. coli.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:2,000, IF:1:50-1:250, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, 20 % glycerol and 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody solution should be gently mixed before use.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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: "Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation." in: Development (Cambridge, England), Vol. 144, Issue 8, pp. 1518-1530, (2017) (PubMed).
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: "Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation." in: Development (Cambridge, England), Vol. 144, Issue 8, pp. 1518-1530, (2017) (PubMed).
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- beta-Catenin
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Hintergrund
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Goat polyclonal antibody to Catenin (cadherin-associated protein), beta 1. Beta Catenin is a 88 kDa protein and is a key downstream effector in the Wnt signalling pathway. It is involved in early embryonic development and tumorigenesis. Beta Catenin is part of a complex of proteins that constitute adherens junctions, necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. This protein anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.
cadherin-associated protein, CTNNB, CTNNB1, MRD19, armadillo antibody.
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Molekulargewicht
- 88 kDa
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Pathways
- Peptide Hormone Metabolism
Target
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