Huntingtin Antikörper (AA 85-200)
Kurzübersicht für Huntingtin Antikörper (AA 85-200) (ABIN6254174)
Target
Alle Huntingtin (HTT) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 85-200
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Verwendungszweck
- Anti-HTT
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Sequenz
- PLHRPKKELS ATKKDRVNHC LTICENIVAQ SVRNSPEFQK LLGIAMELFL LCSDDAESDV RMVADECLNK VIKALMDSNL PRLQLELYKE IKKNGAPRSL RAALWRFAEL
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Spezifität
- Reacts huntingtin protein, amino acids 85-200. The antibody recognizes wild type and mutant huntingtin.
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Produktmerkmale
- Huntingtin
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Aufreinigung
- Epitope affinity purified
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Immunogen
- Purified recombinant peptide derived from within residues 85 to 200 aa of human HTT produced in E. coli
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:2,000, IF:1:500-1:2,000, IHC-P:1:500-1:2,000, IHC-F:1:500-1:2,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, 20 % glycerol and 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody solution should be gently mixed before use.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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: "Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease." in: Glia, Vol. 64, Issue 11, pp. 1841-56, (2018) (PubMed).
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: "Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease." in: Glia, Vol. 64, Issue 11, pp. 1841-56, (2018) (PubMed).
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- Huntingtin (HTT)
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Andere Bezeichnung
- HTT
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Hintergrund
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Huntingtin is a protein linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons.
HD, HTT and IT15 antibody.
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Pathways
- PI3K-Akt Signalweg, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
Target
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