EGFR Antikörper (C-Term)
Kurzübersicht für EGFR Antikörper (C-Term) (ABIN6254171)
Target
Alle EGFR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- anti-ERBB1
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Sequenz
- SHQISLDNPD YQQDFFPKEA KPNGIFKGST AENAEYLRVA PQSSEFIGA
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Spezifität
- This antibody gives a positive signal in the following human (HaCat, SKOV3 and H69) whole cell lysates by Western blot.
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Produktmerkmale
- Epidermal growth factor receptor
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Aufreinigung
- Epitope affinity purified
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Immunogen
- Purified recombinant peptide derived from within residues 1,162 aa to the C-terminus of human ERBB1 produced in E. coli.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, 20 % glycerol and 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody solution should be gently mixed before use.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Andere Bezeichnung
- ERBB1
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Hintergrund
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Goat polyclonal antibody to ERBB1. ERBB1 is a transmembrane glycoprotein that is a member of the protein kinase superfamily and a receptor for members of the epidermal growth factor family. It is a cell surface protein that binds to epidermal growth factor inducing receptor dimerization and tyrosine autophosphorylation and leading to cell proliferation. This receptor has been associated with cancer. Different protein isoforms encoded by multiple alternatively spliced transcript variants have been found for this gene.
EGFR, epidermal growth factor receptor, ERBB, HER1, mENA, NISBD2PIG61, antibody.
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
Target
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