Insulin Receptor Antikörper (C-Term)
Kurzübersicht für Insulin Receptor Antikörper (C-Term) (ABIN6254165)
Target
Alle Insulin Receptor (INSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- anti-INSR
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Sequenz
- KAPESEELEM EFEDMENVPL DRSSHCQREE AGGRDGGSSL GFKRSYEEHI PYTHMNGGKK NGRILTLPRS NPS
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Spezifität
- Using liver, HeLa and Skov3 cell lysates detects a 180 kDa band by Western blot.
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Produktmerkmale
- Insulin receptor
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Aufreinigung
- Epitope affinity purified
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Immunogen
- Purified recombinant peptide within residues 1310 aa to the C-terminus of human INSR produced in E. coli.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:5,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, 20 % glycerol and 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody solution should be gently mixed before use.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- Insulin Receptor (INSR)
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Andere Bezeichnung
- INSR
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Hintergrund
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Goat polyclonal antibody to insulin receptor. INSR is a receptor tyrosine kinase. Preprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. The insulin signalling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein is activated by the binding of insulin or other ligands to this receptor.
CD220, HHF5, insulin receptor antibody.
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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