CD22
Reaktivität: Human
FACS, WB, ELISA, IF, IP
Wirt: Kaninchen
Monoclonal
DM13
unconjugated
Applikationshinweise
immunohistochemistry on cytospots, immunohistochemistry on frozen tissue sections
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
4 °C
Target
CD22
(CD22 Molecule (CD22))
Andere Bezeichnung
CD22
Hintergrund
Antigen distribution: CD22 is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface simultaneously with surface IgD, and is found on most mature B cells. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via surface Ig increases CD22 expression [1]. CD22 reacts with most B cell leukemias including Hairy Cell Leukemia (HCL) and B cell lymphomas. Cellular Expression: Pan B cells, (surface and cytoplasmatic staining).