ITGAL Antikörper

Produktnummer ABIN6252976

Der Maus Monoklonal anti-ITGAL Antikörper (Klon TS1-22) (ABIN6252976) detektiert spezifisch ITGAL in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ITGAL Antikörper (ABIN6252976)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: TS1-22

Produktdetails anti-ITGAL Antikörper

Verwendungszweck: CD11a Unconjugated Antibody

Produktmerkmale: The clone recognizes a 170-180 kD alpha chain of a type I transmembrane glycoprotein also known as CD11a or LFA-1a. It is also known as LFA-1α. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. CD11a is abundantly expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils but does not express by the non-hematopoietic tissues and platelets. Up-regulation of CD11a on activated lymphocytes is required to induce their immune response. Absence or reduced CD11a expression on tumor cells helps to escape from regular immune surveillance and it may be one of reason of in vivo tumor generation.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human HLA-DRCTL line cytolytic Tlymphocytes

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: CD11a

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex