Retinoblastoma Protein (Rb) Antikörper

Produktnummer ABIN6252811

Der Maus Monoklonal anti-Retinoblastoma Protein (Rb) Antikörper wird verwendet zum Nachweis von Retinoblastoma Protein (Rb) in Proben von Human und Maus. Er wurde validiert für WB, IP und IHC (p).

Kurzübersicht für Retinoblastoma Protein (Rb) Antikörper (ABIN6252811)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB1-1754

Produktdetails anti-Retinoblastoma Protein (Rb) Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: A human recombinant protein was used as the immunogen for this Rb antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1 μg/mL

IP: 1-2 μg/500 μg protein lysate

IHC (FFPE): 1-2 μg/mL for 30 min at RT

Titering of the Rb antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu Retinoblastoma Protein (Rb)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Andere Bezeichnung: Retinoblastoma / Rb

Hintergrund: Recognizes a 105  kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.

Gen-ID: 5925

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases