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HLA-ABC Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HLA-ABC in FACS, IF und WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Non-Human Primate.
Produktnummer ABIN6252708

Kurzübersicht für HLA-ABC Antikörper (ABIN6252708)

Target

Alle HLA-ABC Antikörper anzeigen
HLA-ABC

Reaktivität

  • 71
  • 28
  • 21
  • 19
  • 17
  • 13
  • 13
  • 12
  • 11
  • 11
  • 7
  • 7
  • 6
  • 5
  • 2
  • 1
Human, Maus, Non-Human Primate

Wirt

  • 58
  • 10
  • 4
Maus

Klonalität

  • 62
  • 9
Monoklonal

Konjugat

  • 31
  • 8
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HLA-ABC Antikörper ist unkonjugiert

Applikation

  • 55
  • 19
  • 17
  • 13
  • 10
  • 9
  • 9
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Klon

246-B8-E7
  • Aufreinigung

    Protein G affinity chromatography

    Immunogen

    Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Western blot: 1-2 μg/mL

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.2 mg/mL

    Buffer

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Target

    HLA-ABC

    Andere Bezeichnung

    HLA-ABC

    Hintergrund

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    UniProt

    P01889, P30443, P30499

    Pathways

    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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