FSHR Antikörper
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- Target Alle FSHR Antikörper anzeigen
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FSHR Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- A human recombinant protein was used as the immunogen for this FSHR antibody.
- Klon
- FSHR-1400
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product FSHR Primärantikörper
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- Applikationshinweise
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Flow Cytometry: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FSHR antibody to be titered up or down for optimal performance. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Target
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- Andere Bezeichnung
- FSH Receptor (FSHR Produkte)
- Synonyme
- FSHRO antikoerper, LGR1 antikoerper, ODG1 antikoerper, FSH-R antikoerper, eFSHR antikoerper, FSHRE antikoerper, fshr antikoerper, FSHR antikoerper, fshr-A antikoerper, GTHR-I antikoerper, zfGTHR-I antikoerper, LOC100304505 antikoerper, follicle stimulating hormone receptor antikoerper, follicle stimulating hormone receptor L homeolog antikoerper, follicle-stimulating hormone receptor antikoerper, FSHR antikoerper, fshr antikoerper, Fshr antikoerper, fshr.L antikoerper, Bm1_17785 antikoerper, LOC100304505 antikoerper
- Hintergrund
- Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.
- Gen-ID
- 2492
- UniProt
- P23945
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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