ROS1 Antikörper
Kurzübersicht für ROS1 Antikörper (ABIN6243980)
Target
Alle ROS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogen
- This ROS1 antibody is generated from a mouse immunized with a recombinant protein of human ROS1.
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Isotyp
- IgG1 kappa
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anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 1945-2222) antibody
ROS1 Reaktivität: Human WB, ELISA, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 1945-2222) antibodyROS1 Reaktivität: Human WB Wirt: Maus Monoclonal C1 unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 2231-2347) antibodyROS1 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 33-63), (N-Term) antibodyROS1 Reaktivität: Human WB, IHC (p), IF, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 79-248) antibodyROS1 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 1744-1777), (C-Term) antibodyROS1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB50575 unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (C-Term) antibodyROS1 Reaktivität: Human, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 1937-2210) antibodyROS1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (C-Term) antibodyROS1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC: 1:250. WB: 1:4000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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Andere Bezeichnung
- ROS1
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Hintergrund
- Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
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Molekulargewicht
- 263915
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UniProt
- P08922
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Pathways
- RTK Signalweg
Target
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