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ROS1 Antikörper (C-Term)

ROS1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030232
  • Target Alle ROS1 Antikörper anzeigen
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    Bindungsspezifität
    • 16
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 43
    • 28
    • 25
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 49
    • 5
    • 1
    Kaninchen
    Klonalität
    • 49
    • 6
    Polyklonal
    Konjugat
    • 23
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ROS1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 19
    • 14
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antigen affinity purified
    Immunogen
    This ROS1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1744-1777 amino acids from the C-terminal region of human ROS1.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ROS1 Primärantikörper
  • Applikationshinweise
    Titration of the ROS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the ROS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    Andere Bezeichnung
    ROS1 (ROS1 Produkte)
    Synonyme
    MCF3 antikoerper, ROS antikoerper, c-ros-1 antikoerper, ROS1C antikoerper, Ros-1 antikoerper, c-ros antikoerper, ROS proto-oncogene 1, receptor tyrosine kinase antikoerper, ROS proto-oncogene 1 , receptor tyrosine kinase antikoerper, Ros1 proto-oncogene antikoerper, ROS1 antikoerper, Ros1 antikoerper
    Hintergrund
    Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
    UniProt
    P08922
    Pathways
    RTK Signalweg
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