SPPL2B Antikörper (AA 126-160)
Kurzübersicht für SPPL2B Antikörper (AA 126-160) (ABIN6243976)
Target
Alle SPPL2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 126-160
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This SPPL2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 126-160 amino acids from human SPPL2B.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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Andere Bezeichnung
- SPPL2B
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Hintergrund
- Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF- alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.
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Molekulargewicht
- 64644
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UniProt
- Q8TCT7
Target
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