ATG16L1 Antikörper

Produktnummer ABIN6243484

Dieses Anti-ATG16L1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ATG16L1 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ATG16L1 Antikörper (ABIN6243484)

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATG16L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 54CT27-2-6

Produktdetails anti-ATG16L1 Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged ATG16L1 protein(Fragment) was used to produced this monoclonal antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:60. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ATG16L1 Antikörper (ABIN6243484)

Martinez-Outschoorn, Trimmer, Lin, Whitaker-Menezes, Chiavarina, Zhou, Wang, Pavlides, Martinez-Cantarin, Capozza, Witkiewicz, Flomenberg, Howell, Pestell, Caro, Lisanti, Sotgia: "Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 17, pp. 3515-33, (2010) (PubMed).

Details zu ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Andere Bezeichnung: ATG16L1

Hintergrund: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 68265

NCBI Accession: NP_001177195, NP_001177196, NP_060444, NP_110430, NP_942593

UniProt: Q676U5

Pathways: Autophagie