MAPK12 Antikörper (AA 319-353)

Produktnummer ABIN6243201

Der Kaninchen Polyklonal anti-MAPK12 Antikörper wird verwendet zum Nachweis von MAPK12 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für MAPK12 Antikörper (AA 319-353) (ABIN6243201)

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB47232

Produktdetails anti-MAPK12 Antikörper

Bindungsspezifität: AA 319-353

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This (DANRE) mapk12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 319-353 amino acids of DANRE mapk12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu MAPK12

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Andere Bezeichnung: mapk12

Hintergrund: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets (By similarity).

Molekulargewicht: 41971

UniProt: O42376

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteine