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MME Antikörper (AA 472-505)

Name: MME Antikörper (AA 472-505)
SKU: ABIN6243087
Price: 445.5 EUR
Availability: InStock

MME Reaktivität: Human FACS, WB, IHC (p) Wirt: Maus Monoclonal 965CT9-1-1 unconjugated

All lanes : Anti-E Antibody (Center) at 1:4000 dilution Lane 1: Human placenta lysate Lane 2: Ramos whole cell lysate Lane 3: Human kidney lysate Lysates/proteins at 20 μg per lane. (MME Antikörper (AA 472-505))

Immunohistochemical analysis of paraffin-embedded human kidney tissue using (ABIN6243087 and ABIN6577253) performed on the Leica® BOND RXm. (MME Antikörper (AA 472-505))

IHC (p)

Immunohistochemical analysis of paraffin-embedded Human kidney section using Pink1 (ABIN6243087 and ABIN6577253). (MME Antikörper (AA 472-505))

IHC

Overlay histogram showing Jurkat cells stained with (ABIN6243087 and ABIN6577253)(green line). (MME Antikörper (AA 472-505))

FACS

4 Abbildungen

Produktnummer ABIN6243087

Datenblatt (PDF)

Target Alle MME Antikörper anzeigen

MME (Membrane Metallo-Endopeptidase (MME))
Bindungsspezifität
16

14

10

8

8

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 472-505
Reaktivität
213

58

50

3

2

2

2

2

2

1

1

1

1
Human
Wirt
111

108

2
Maus
Passende Sekundärantikörper
Klonalität
115

105

2
Monoklonal
Konjugat
108

19

19

14

9

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MME Antikörper ist unkonjugiert
Applikation
132

100

80

69

38

29

21

21

13

13

10

8

6

5

5

3

2

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This MME antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 472-505 amino acids from the Central region of human MME.

Klon

965CT9-1-1

Isotyp

IgG1 kappa

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Applikationshinweise

WB: 1:4000. IHC: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Target

MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung

MME (MME Produkte)

Synonyme

CALLA antikoerper, CD10 antikoerper, NEP antikoerper, SFE antikoerper, 6030454K05Rik antikoerper, C85356 antikoerper, Nep antikoerper, neprilysin antikoerper, membrane metalloendopeptidase antikoerper, membrane metallo endopeptidase antikoerper, membrane metallo-endopeptidase antikoerper, MME antikoerper, Mme antikoerper

Substanzklasse

Chemical

Hintergrund

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675, PubMed:< a href="http://www.uniprot.org/citations/8168535" target="_blank">8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:< a href="http://www.uniprot.org/citations/17101991" target="_blank">17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:< a href="http://www.uniprot.org/citations/2531377" target="_blank">2531377, PubMed:< a href="http://www.uniprot.org/citations/2972276" target="_blank">2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:< a href="http://www.uniprot.org/citations/20876573" target="_blank">20876573).

Molekulargewicht

85514

UniProt

P08473

Pathways

RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration