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Sonic Hedgehog Antikörper (C-Term)

SHH Reaktivität: Maus WB, FACS Wirt: Kaninchen Polyclonal RB51214 unconjugated
Produktnummer ABIN6242829
  • Target Alle Sonic Hedgehog (SHH) Antikörper anzeigen
    Sonic Hedgehog (SHH)
    Bindungsspezifität
    • 15
    • 11
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 397-431, C-Term
    Reaktivität
    • 61
    • 53
    • 40
    • 17
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 72
    • 10
    • 8
    • 1
    • 1
    Kaninchen
    Klonalität
    • 65
    • 27
    Polyklonal
    Konjugat
    • 52
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sonic Hedgehog Antikörper ist unkonjugiert
    Applikation
    • 72
    • 32
    • 25
    • 14
    • 13
    • 11
    • 10
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Shh antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 397-431 amino acids from the C-terminal region of mouse Shh.
    Klon
    RB51214
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SHH Primärantikörper
  • Applikationshinweise
    WB: 1:1000. FC: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    Sonic Hedgehog (SHH)
    Andere Bezeichnung
    Shh (SHH Produkte)
    Synonyme
    HHG1 antikoerper, HLP3 antikoerper, HPE3 antikoerper, MCOPCB5 antikoerper, SMMCI antikoerper, TPT antikoerper, TPTPS antikoerper, 9530036O11Rik antikoerper, Dsh antikoerper, Hhg1 antikoerper, Hx antikoerper, Hxl3 antikoerper, M100081 antikoerper, fc83d08 antikoerper, shh antikoerper, syu antikoerper, vhh-1 antikoerper, vhh1 antikoerper, wu:fc83d08 antikoerper, Xhh antikoerper, hedgehog antikoerper, xshh antikoerper, SHH antikoerper, twh antikoerper, twhh antikoerper, sonic hedgehog antikoerper, sonic hedgehog a antikoerper, sonic hedgehog L homeolog antikoerper, sonic hedgehog protein A antikoerper, sonic hedgehog b antikoerper, SHH antikoerper, Shh antikoerper, shha antikoerper, shh.L antikoerper, shh antikoerper, shhb antikoerper
    Hintergrund
    Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity).
    Molekulargewicht
    47773
    UniProt
    Q62226
    Pathways
    Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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